Abnormal LFT’s

  • Abnormal liver function tests (LFTs) indicate potential liver dysfunction or damage.
  • Common LFTs include alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), and bilirubin.
  • Elevated ALT and AST levels suggest hepatocellular damage, often due to conditions like hepatitis or liver inflammation.
  • Elevated ALP levels may indicate cholestasis or obstruction of bile flow, which can be caused by gallstones,  liver or pancreatic tumors.
  • Elevated bilirubin levels may signify liver disease, bile duct obstruction, or hemolysis (breakdown of red blood cells).
  • Causes of abnormal LFTs include viral hepatitis, fatty liver disease, alcohol abuse, autoimmune liver diseases, medications, and metabolic disorders.
  • Diagnosis involves further evaluation with ultrasound, CT and MRI scans, liver biopsy, and additional blood work.
  • Treatment depends on the underlying cause and may involve lifestyle changes, medications, or surgery.
  • Regular monitoring of LFTs is crucial for tracking liver health and managing any underlying conditions.

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