- Abnormal liver function tests (LFTs) indicate potential liver dysfunction or damage.
- Common LFTs include alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), and bilirubin.
- Elevated ALT and AST levels suggest hepatocellular damage, often due to conditions like hepatitis or liver inflammation.
- Elevated ALP levels may indicate cholestasis or obstruction of bile flow, which can be caused by gallstones, liver or pancreatic tumors.
- Elevated bilirubin levels may signify liver disease, bile duct obstruction, or hemolysis (breakdown of red blood cells).
- Causes of abnormal LFTs include viral hepatitis, fatty liver disease, alcohol abuse, autoimmune liver diseases, medications, and metabolic disorders.
- Diagnosis involves further evaluation with ultrasound, CT and MRI scans, liver biopsy, and additional blood work.
- Treatment depends on the underlying cause and may involve lifestyle changes, medications, or surgery.
- Regular monitoring of LFTs is crucial for tracking liver health and managing any underlying conditions.
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